The
primary goal of this website is to demonstrate the suitability of semblance
hypothesis in explaining internal sensation of memory and other brain
functions. This hypothesis was published in 2007 and revised
editions were published in 2008 and 2010. In contrast to the conventional
approaches to study memory by examining molecular and electrophysiological
changes taking place at the time of associative learning, the present work
has examined possible basic units of internal sensations formed during
memory retrieval and traced it back to potential changes occurring during
associative learning. Using this approach, higher
brain functions that are intrinsic to the system are reduced to basic units
of internal sensations that can be formed from synaptic level functions
(physical mechanism). Need for this approach and feasibility to test the
operation of similar units in physical systems is
explained.
By this
approach, most of the findings by different faculties of brain research can
be explained as interconnected phenomena. These include gene expression
associated with learning (Biochemistry), dendritic spine changes
(Neurobiology), LTP (Electrophysiology), place cell firing (Systems
neuroscience), consolidation of memory (Psychology) and association of memory with consciousness (Consciousness studies).
Most importantly, it provides a mechanism for memory retrieval at
physiological time scales.
Recent research findings from different laboratories
are examined in terms of the present hypothesis and analyses have been
posted.
